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Bristol Myers Squibb Scientist, Potency & Functional Characterization - Cell Therapy in Seattle, Washington

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Cell Therapy is one of the most groundbreaking new forms of cancer treatments being studied today. With therapies only in their infancy and BMS’s continued investment in our Cell Therapy capabilities, the growth potential of this science, your career, and the ability to help patients are incredible.


The Potency and Functional Characterization department is seeking a Scientist who will lead development of molecular methods ( e.g. RT-qPCR) that assess autologous and allogenic cell therapies which are currently undergoing clinical trials, including CAR T cell products. The Scientist will be responsible for developing highly impactful methods, including QC methods for lot release testing as well as characterization methods that support process development and comparability assessments. These methods will be used to further the understanding of cell therapies, support development of the manufacturing processes, and/or QC release of the drug product. The Scientist will have extensive hands-on experience in assay development and possess excellent communication skills in order to work on projects requiring close collaboration with other groups, such as discovery research, product sciences, process development, and QC. Additionally, the Scientist will interface with external vendors ( e.g. CMO’s) for the successful management of transferred analytical methods. The Scientist will be passionate about developing novel medicines, thrive in an intellectually challenging environment, and enjoy collaborating with a team of likeminded Scientists.

REQUIRED COMPETENCIES: Knowledge, Skills, and Abilities:


BS, MS or PhD in Molecular Biology, Immunology, Microbiology, Cell Biology, Cancer Biology, Biochemistry, or related field.


  • PhD with 0-3 years, or MS with 8+ years, or BS with 10+ years of relevant industry experience.

  • Proven experience with qPCR, RT-qPCR, and/or ddPCR.

  • Strong problem-solving ability to troubleshoot complex technical and scientific problems.

  • Experience with aseptic technique, mammalian cell culture, primary human cells, and cryopreservation.

  • Experience with writing technical and regulatory documents for interdepartmental use and external vendors ( e.g. CMO’s).

  • Strong attention to detail.

  • Outstanding written and oral communication skills.

  • Work effectively in a collaborative team setting.

  • Ability to work in a rapidly changing environment with frequent changes in priorities.

Preferred Qualifications

  • Knowledge of T cell biology

  • Knowledge of viral vectors and assessment of replication competency by co-culture methods

  • Experience with developing multiplex PCR reactions

  • Experience with single cell genomics

  • Understanding of immunology and cell-based assays as applied to the cell therapy field

  • Experience with data analysis and interpretation using software (e.g. Softmax Pro, Gen5, Maestro, Excel).

  • Familiarity with statistical analysis and design on experiments (DoE) using JMP software.

  • Track record of successful transfer and management of analytical methods


  • Subject matter expert responsible for developing robust analytical methods and expanding product understanding

  • Independently develop and execute cell-based and molecular assays

  • Identify issues, lead troubleshooting experiments, and determine solutions with minimal to no guidance

  • Train users on method execution, data analyses, and proper use of instrumentation

  • Lead qualification and transfer of analytical methods to external stakeholders

  • Routinely present work at team, technical team, and department meetings

  • Preparation and qualification of critical reagents

  • Maintain meticulous laboratory notebooks

  • Analyzing, interpreting, and presenting data to internal and external stakeholders (Power Point Presentations)

  • Author, review and approve technical documents, including methods, protocols, reports, and SOPs

  • Deliver lifecycle-managed analytical methods for multiple programs with an understanding of ICH/FDA/EMEA best practices and current thinking.

  • Facilitate smooth operation of the laboratory, including ordering, assisting in the cryopreservation of cellular material, sample management, etc.

If you want to challenge yourself, accelerate your career, and give new hope to patients, there’s no better place than here with our Cell Therapy team. Full of incredible and dedicated team members, those working on CAR-T and other forms of Cell Therapy are transforming patients’ lives through science. From studying individualized cell lines to making brand new discoveries, this bold and personal discipline allows you to grow your career while making a lasting impact on the field of medicine. Join us today.


Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or any part of the recruitment process direct your inquiries to Visit to access our complete Equal Employment Opportunity statement.

Company: Bristol Myers Squibb

Req Number: R1543760

Updated: 2021-07-29 07:02:22.176 UTC

Location: Seattle,Washington

Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.