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Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .

The Cancer Immunology and Cellular Therapy Thematic Research Center (CICT) is one of the fundamental research and early development engines delivering therapeutics to patients. Our mission is to drive leadership in the use of immune effector cell-based therapies in hematological and solid cancers. Within CICT, the Cell Therapy Process Research and Engineering (CT-PRE) team works at the exciting interface of engineered T-cell biology and cell therapy process development, in close collaboration with colleagues across the Research and Development organizations, with the goal of advancing novel innovative platforms from early concept design towards implementation for pipeline assets. "

The CT-PRE team is seeking a highly motivated, dynamic, self-driven and collaborative individual to contribute to the exploration and early process development of next generation cell therapies." This team is responsible for accelerating the assessment of novel drug assets in the preclinical pipeline from research to full development. The candidate will conceptualize, design , and execute lab experiments, both individually as well as with other lab scientists through efficient collaboration and teamwork. The successful candidate is expected to be both scientifically creative in assessing novel gene delivery and cell engineering strategies, and technically adept at leveraging experience from existing cell therapy principles to enable drug process manufacturing success. Scientific understanding of gene-edited CAR T-cell immunotherapy is required . "

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Position Responsibilities" "

In the role as a Scientist within the CT-PRE Team, the ideal candidate will apply scientific principles to engineer T cells for drug process development. This includes:" " "

• Designing lab experiments that utilizes novel gene delivery and cell engineering modalities to assess drug product manufacturing feasibility. " "

• Leading and executing lab experiments that include assessing human T-cell selection , activation/expansion, washing, and gene editing techniques. "

• Leveraging knowledge of T-cell biology to a ssess new technolog y feasibility for next-gen cell therapy process development .

• Leveraging engineering principles to scale - up benchtop CAR T cell production protocols into manufacturing-like scale drug development process .

• Documenting experimental execution in electronic lab notebook for demonstrating repeatability and robustness of developed processes. " "

• Analyzing data, and clearly and concisely communicating data to research and development functional teams." "

• Representing our group at cross-functional project team(s), effectively relaying pertinent information to and from group." "

• Training junior team members as needed in laboratory techniques ." "

• Strong foundational principles to scientific approach shown through excellent critical thinking skills, problem solving and troubleshooting skills, and attention to details. " "

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Basic Qualifications:" " "

Bachelor's Degree " "

• 5+ years of academic and / or industry experience" " "

Or " "

Master's Degree" " "

• 3+ years of academic and / or industry experience" " "

Or " "

Ph.D. or equivalent advanced degree in the Life Sciences " "

• No experience necessary " "

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Preferred Qualifications "

• Ph.D. in bio/chemical engineering , molecular engineering, or related discipline, specializing in cell therapy or T-cell biolog y .

• Extensive understanding and hands-on experience in aseptic techniques used in primary T-cell selection , activation, electroporation and gene editing, expansion, cryopreservation, etc." "

• Up-to-date knowledge of CRISPR-based gene editing technologies for cell therapies (viral and non-viral)." "

• Working knowledge of analyzing and interpreting data from cellular and molecular assays (e.g. flow cytometry, ddPCR ) .

• Familiarity with Design of Experiments ( DoEs ) and statistical analysis is p referred . " "

• A team player who can also thrive in a fast-paced, innovative environment through individual excellence." "

• Strong communication skills as demonstrated by first-author, peer-reviewed publications and oral conference presentations.

The starting compensation for this job is a range from $97,000 - $121,000 plus incentive cash and stock opportunities (based on eligibility).

The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed.

Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit our BMS Career Site.

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.

#LI-Onsite

If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as Transforming patients' lives through science™ , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ (https://careers.bms.com/eeo-accessibility) eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Company: Bristol-Myers Squibb

Req Number: R1584393

Updated: 2024-09-12 05:37:42.508 UTC

Location: Seattle-WA

Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.