University of Washington RESEARCH SCIENTIST/ENGINEER 1 in Seattle, Washington
Req #: 221440
Posting Date: 05/03/2023
Closing Info: Open Until Filled
Salary: $3887 - $7765 per month
Shift: First Shift
Notes: As a UW employee, you will enjoy generous benefits and work/life programs. For a complete description of our benefits for this position, please visit our website, click here. (https://hr.uw.edu/wp-content/uploads/sites/3/2018/02/benefits-professional-staff-librarians-academic-staff-20230119_a11y.pdf )
As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem solving skills and dedication to build stronger minds and a healthier world.
UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits and natural beauty.
The University of Washington School of Pharmacy is ranked nationally in the top schools of Pharmacy. At the School of Pharmacy, we are committed to educating the next generation of leaders in pharmacy, pharmaceutical research and health care – while seeking to ensure the safe, rational and cost-effective use of medicines.
The Department of Pharmaceutics in the School of Pharmacy has an outstanding opportunity for a highly motivated Research Scientist/Engineer 1. . Under the guidance of the Principal Investigators (Jash Unadkat), the Research Scientist/Engineer I will be responsible for managing the lab, and running experiments focused on predicting the in vivo disposition of drugs based on in vitro studies (e.g. qPCR, quantitative targeted proteomics, transporter/enzyme activity assays). While this position will generally follow established standard operating procedures of the research laboratory, the incumbent should be highly flexible and work well in a dynamic research environment. Strong attention to detail, record keeping and quantitation is required.
To predict the disposition of medicinal drugs in humans based on in vitro studies using cell culture and quantitative techniques such as qPCR, quantitative targeted proteomics, and activity assays of transporters and enzymes.
AND RESPONSIBILITIES: Research - 95%
Conduct BSL2 level research on human tissues or primary cells, cells expressing human proteins; specific duties will include working with clinical research coordinators to procure human tissue, process tissue, prepare, propagate, and preserve primary cells from human tissues
Using primary or continuous cells expressing human proteins, conduct molecular profiling of gene expression, immunostaining of the cells, conduct LC-MS/MS assays to quantify the proteins or medicinal drugs and work with hazardous chemicals/drugs
Collect and organize electronic copies of laboratory protocols, SOPs, chemical inventories, and lab personnel assigned duties; manage all safety aspects of the laboratory
Review scientific journals, abstracts and other literature concerning experimental procedures and confer with Principal Investigators to implement experimental procedures
Perform basic data analysis and prepare reports summarizing experimental research results
Keeping detailed laboratory notebook records of research studies
Operate complex and highly specialized laboratory instruments and equipment in support of research activities; may instructs others in their use
Acquire and analyze data for manuscript publication; use standard software to analyze data such as Excel, GraphPad/Prism
Review the work of laboratory personnel; instruct other lab personnel on research techniques listed above
Attend lab meetings and research seminars as relevant to laboratory activity
Assist lab personnel in conduct of their research Administration
Other duties as assigned MINIMUM REQUIREMENTS:
Bachelor's degree in chemistry, biology, or a related field
At least 3 to 12 months of research experience in the areas listed above or a related areaEquivalent education/experience will substitute for all minimum qualifications except where there are legal requirements such as license/certification/registration. ADDITIONAL REQUIREMENTS:
Excellent records-keeping ability, and strong verbal and written communication skills
Preference will be given to applicants with experience in cell culture and qPCR
Excellent quantitative skills
Works well with others in a fast-paced team environment.
Strong attention to detail and willingness to learn
Willing to conduct routine laboratory tasks DESIRED QUALIFICATIONS:
Willingness to learn new techniques, interested in writing and publishing manuscripts, interested in quantitative sciences Application Process: The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Workforce Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to, among other things, race, religion, color, national origin, sexual orientation, gender identity, sex, age, protected veteran or disabled status, or genetic information.
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