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University of Washington RESEARCH SCIENTIST/ ENGINEER 3 in Seattle, Washington

Req #: 226405

Department: DEPARTMENT OF LABORATORY MEDICINE AND PATHOLOGY

Posting Date: 02/02/2024

Closing Info: Open Until Filled

Salary: $5,427- $9,000 per month

Shift: First Shift

Notes: As a UW employee, you will enjoy generous benefits and work/life programs. For a complete description of our benefits for this position, please visit our website, click here. (https://hr.uw.edu/wp-content/uploads/sites/3/2018/02/benefits-professional-staff-librarians-academic-staff-20230119_a11y.pdf)

This posting will be used to fill additional openings. The salary range for this position has been updated to $5,427- $9,000 per month from the previously posted range of $5,427 - $11,051 per month on 2/23/24. Please note that this position has been refreshed. If you have already submitted your application, you need not submit it again, as it has already been received.

As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem solving skills and dedication to build stronger minds and a healthier world.

UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits and natural beauty.

The Department of Laboratory Medicine and Pathology has 2 outstanding openings for Research Scientst/ Engineer 3.

This position reports to Dr. Alex Greninger in the Greninger Lab. This position supports viral genomics and determinants of viral growth.

DUTIES & RESPONSIBILITIES Experiment/Research/Project Management (80%) • Creation and optimization of metagenomic next-generation sequencing libraries for unbiased pathogen detection and viral genome recovery. Genome finishing of novel viruses, including optimization of high-throughput methods. • Development of next-generation sequencing analysis pipelines for taxonomical analysis and viral genome visualization. • Development of phage display serological profiling tools to investigate high-resolution interrogation of serological response, including creation of analysis tools. • Perform high-level viral culture in novel culture models and reverse genetics work, analyze data compile results and draft reports for incoming research awards and contracts • Supervise and analyze quantitative viral load determination using RT-qPCR, qPCR, ddPCR, including optimization of new assays • Supervise performance of molecular procedures including but not limited to real-time PCR, Sanger sequencing, PCR product detection DNA sequencing and next generation sequencing; Perform work accurately, precisely and meet test completion deadlines; • Maintain complete, accurate, legible, secure records. Thoroughly document any modifications using appropriate document and version control. • Analyze experimental data and report to the Director and Lab Supervisor; determine what modifications and follow-up experiments are necessary to generate relevant data; • Identify long and short term goals; initiate research program/projects; • Contribute technical knowledge when initiating new projects to determining feasibility of goals and objectives of the study; • Contribute data and analyses for grant submissions; • Perform preliminary experiments for assay development; • Work with R, python, Geneious, Excel, and bash command line; • Accommodate schedule changes to cooperatively accomplish required daily work, coordinate with Laboratory supervisor/manager; • Collaborate with research team to create opportunities and ancillary research projects to enhance technical assay methodology or content through the expansion of existing or development of new projects; • Review the scientific process of each research project, analyze issues, understand scientific procedures and statistical analysis; report data using graphs and charts; • Prepare manuscripts for publication; • Provide ongoing feedback; identify development opportunities and actively solicit input on work methods;

Other Duties (20%) • Provide ongoing feedback; identify development opportunities and actively solicit input on work methods; • Trains and monitors new employees and guest technicians in experimental procedures and assays, laboratory safety and database maintenance; • Perform other duties as required.

MINIMUM REQUIREMENTS:
Bachelor's degree in molecular biology, virology, genomics AND 4 years of relevant experience, OR Equivalent combination of education/experience.

Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration. DESIRED:
• Prior mammalian cell culture experience • Prior coding experience • Previous experience with next-generation sequencing analysis and genomics • Strong written and communication skills • Ability to problem-solve and troubleshoot • Proficient at R, python, and/or bash. • Experience with other herpesvirus reverse genetics systems • Data analysis skills with basic statistical knowledge

Application Process:

The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Work Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.

University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to, among other things, race, religion, color, national origin, sexual orientation, gender identity, sex, age, protected veteran or disabled status, or genetic information.

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