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Seattle Children’s Hospital Postdoctoral Fellow - PhD, Research in Seattle, Washington

Postdoctoral Fellow - PhD, ResearchJob ID2021-42021Area of InterestResearch & DevelopmentLocation Name307 WestlakeFTE/Hours per pay period1.0 FTE (80 hours per bi-weekly pay periods)Work StatusRegularDepartmentGlobal Infectious DiseaseShiftDay ShiftPrimary Location : CitySeattlePrimary Location : State/ProvinceWAAbout UsHope. Care. Cure. These three simple words capture what we do at Seattle Children's -- to help every child live the healthiest and most fulfilling life possible. Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECUREOur founding promise to the community is as valid today as it was over a century ago: we will care for all children in our region, regardless of the families' ability to pay. Together, we deliver superior patient care, advance new discoveries and treatments through pediatric research, and serve as the pediatric and adolescent, academic medical center for Washington, Alaska, Montana and Idaho - the largest region of any children's hospital in the country.In 2020, U.S. News & World Report once again ranked Seattle Children's among the nation's best children's hospitals - for the 27th year in a row. We received national rankings in all 10 specialty areas evaluated by U.S. News & World Report, and are honored to be the only pediatric medical center in Washington to be ranked.As a Magnet designated institution, and classified among America's best large employers by Forbes, we recognize the importance of hiring and developing great talent to provide best-in-class care to the patients and families we serve. Our organizational DNA takes form in our core values: Compassion, Excellence, Integrity, Collaboration, Equity and Innovation. Whether it's delivering frontline care to our patients in a kind and caring manner, practicing the highest standards of quality and safety, or being relentlessly curious as we work towards eradicating childhood diseases, these values are the fabric of our culture and community. The future starts here.OverviewWe are seeking scientists with interests and expertise in molecular parasitology for a project on RNA editing in Trypanosomes. This project is focused on the multiprotein complexes that perform this essential posttranscriptional recoding of mitochondrial mRNAs in kinetoplastid parasites. Complementary genetic, molecular, cellular, structure/function, and informatic methods are being used to analyze the functions of the catalytic and non-catalytic protein components of the complexes as well as their interactions with each other, with other complexes, and RNA substrates. This includes analysis of the differential editing which controls the changes in the composition and function of cellular energy generating systems between life cycle stages. The studies are elucidating fundamental aspects of eukaryotic RNA processing and are identifying potential drug targets for neglected tropical diseases caused by these parasites.The research is conducted in the dynamic South Lake Union research environment of Seattle which provides extensive interactions among scientists who are at Seattle Children's Research Institute, Fred Hutchinson Cancer Research Center, University of Washington School of Medicine and other research institutions, all of which are closely located.Both positions require a Ph.D. or equivalent biomedical degree and expertise, along with a strong interest and motivation in the relevant areas.Send expression of interest and CV to: stuartlab.schedule@seattlechildrens.orgRequirementsRequired Education/Experience:- Doctorate degree (PhD/DVM/MD) in