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Responsibilities: Would you like to help kids born with severe heart defects have better lives while also doing exciting science? The Nigam lab (at the Center for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute and the Department of immunology, University of Washington invites applications for a postdoctoral position. Work in the Nigam lab uses basic science and translational approaches to improve the care of children born with severe cardiac defects. The primary focus of the lab seeks to elucidate and find novel treatments for the systemic inflammation that occurs after exposure to cardiopulmonary bypass, which is required for the majority of cardiac surgeries. This project, which has been recently awarded a R01, examines how biomechanical stimuli activate inflammatory responses. As a result, successful candidate will be co-mentored by Dr. Ram Savan in the University of Washington Department of Immunology[].Given the rapid progress of the project, there is a very good potential to be an author on high impact papers. The successful candidate will perform both exacting bench work and analyses on the resulting RNA-Seq/CHiP-Seq/single cell-Seq/CyTOF datasets. The candidate will work closely with a technician and graduate/undergraduate students to plan and supervise several parallel lines of investigation. The candidate will be expected to independently move projects forward, write papers, and apply for F32 or equivalent grants. The ideal candidate will have the ability to perform precise wetlab work and complex bioinformatics analyses. Prior experience with cell culture and R programming would be beneficial. Creative, big-picture thinking and dedication to cardiovascular researchand immune responsesare essential. The selected candidate will join the vibrant research community at CDBRMand Department of immunology, located in a newly renovated building in downtown Seattle. A modern, open lab space, a collegial atmosphere, on-site gym and rooftop garden, and top-of-the-line equipment, office space and meeting rooms make this an ideal training environment. The University of Washington andSeattle Children's Research Institutehave strong scientific interactions with Fred Hutchinson Cancer Research Center, Benaroya Research Institute, Institute for Systems Biology, and Brain Research Institute. Interested applicants should email their CV, brief description of research interests and three references in single PDF file toand. Requirements: Required Education/Experience: -Doctorate degree (PhD/DVM/MD) in specialty area from an accredited university training program - Experience using basic research techniques of specialty area Required Credentials: N/A Preferred: - Previous experience conducting research in the pediatric arena - Experience in protocol and manuscript development and in grant writing Min to Max Hourly Salary: $31.49 - $31.49 /hr Min to Max Annual Salary: $65,500.00 - $65,500.00 /yr Salary Information: This compensation range was calculated based on full-time employment (2080 hours worked per calendar year). Offers are determined by multiple factors including equity, skills, experience, and expertise, and may vary within the range provided. Disclaimer for Out of State Applicants: This compensation range is specific to Seattle, positions located outside of Seattle may be compensated differently depending on various factors. Benefits Information: Seattle Children's offers a generous benefit package, including medical, dental, and vision plans, 403(b), life insurance, paid time off, tuition reimbursement, and more. for more information. About Us: Hope. Care. Cure. These three simple words capture what we do at Seattle Children's - to help every child live the healthiest and most fulfilling life possible. Are you ready to engage with a mission-driven organization that is life-